ethylene glycol msds science lab

Uses x;5rFfu`Wqi?X5UH#|;^ WebEthylene glycol 107-21-1 40% No 1. [31], At a hospital in Bombay, India, patients were admitted to be treated for diverse health problems. Bookshelf 1 State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, People's Republic (ethylene glycol) (Chol-PEG(2000)-COOH) polymer. 2002). National Library of Medicine cause burning sensation in the chest. The episode resulted in the deaths of 21 patients and the discovery of glycerin contaminated with 18.5% v/v of DEG. [30] The next year, an Austrian electric power plant (sterreichische Draukraftwerke) in Carinthia announced that technicians developed a way to produce energy through burning 30 million liters of contaminated wine. It is a colorless, practically odorless, and hygroscopic liquid with a sweetish taste. Paternal effects on the reproductive system and increases in the post-implantation [3] It can be a contaminant in consumer products; this has resulted in numerous epidemics of poisoning since the early 20th century. May cause reproductive and fetal Panamanian officials traced the toothpaste to a local company in the Coln Free Trade Zone. Only approximately 3,000 bottles had been analyzed from the total 6,000 bottles collected. Web107-21-1 Ethylene glycol 90 - 100 111-46-6 Diethylene glycol 0 - 5 Any Concentration shown as a range is due to batch variation. [2][23][32], During the summer months, 47 children were admitted to the Jos University teaching hospital, Nigeria, with anuria, fever and vomiting. The site is secure. Synonyms: We take your privacy seriously. [53][54][55] For the end of the month, the Chinese government committed to investigate the "supposedly" tainted toothpaste that had been recalled in Panama and Dominican Republic, but stated that, as per an essay written in 2000, a toothpaste containing 15.6% was not dangerous. Epub 2016 Apr 30. and transmitted securely. 1 0 obj May cause [65], Ending November 2008, infants started to die after developing unexplained fevers and vomiting. Soon, patients started to present anuria, acidic breathing, hepatomegaly, and unresponsiveness. The industry generally operates to maximize MEG production. When urine analyses for a series of metals, pesticides or their metabolites resulted negative, CDC scientists recalled the Nigeria and Haiti incidents. It is a four carbon dimer of ethylene glycol. 2010 Apr 2;143(1):136-42. doi: 10.1016/j.jconrel.2009.12.020. Accessibility Acute (short-term) exposure of humans to ethylene glycol by ingesting large quantities causes three stages of health effects: central nervous system (CNS) depression, followed by stream InChI=1S/C4H10O3/c5-1-3-7-4-2-6/h5-6H,1-4H2, InChI=1/C4H10O3/c5-1-3-7-4-2-6/h5-6H,1-4H2, Except where otherwise noted, data are given for materials in their, 1937 The Massengill incident (United States). The .gov means its official. 2010 Jul 1;145(1):17-25. doi: 10.1016/j.jconrel.2010.03.007. The most commonly used analytic methods for detection and quantification of ethylene glycol use gas chromatography (GC) coupled to flame ionization detection (FID) or mass spectrometric detectors [Juenke et al. If you are frustrated on your journey back to wellness - don't give up - there is hope. Reproductive toxicity Overexposure may cause reproductive disorder(s) based on tests with laboratory animals. WebProduct Name Ethylene glycol Cat No. Needles (most commonly) (Jacobsen et al. For information, call: 201-796-7100 WebEDTA - Ethylene Diamine TetraAcetic Acid is a transparent water soluble belonging to a class of chelators that bind-chelate-metals. The Dutch authorities assessed a $250,000 fine against Vos B.V., for not alerting anyone when they tested the syrup and found impurities.[42]. (b) Photographs of gels prepared through the DMAP catalyzed oxa-Michael reaction of EG, Increase in the amount of glycerol in the reactant led to the increase in the storage modulus of the as-prepared gels and fully hydrated gels. Although there is limited information about toxicokinetics in humans, observations in mass poisonings and experimental studies suggest the following information: The principal method of absorption is through oral ingestion. Download Printer-Friendly version [PDF 954 KB], After completing this section, you will be able to. In fact, in many hospitals these are only available as send out tests, so results arrive too late for meaningful clinical decision making (Goldfrank LR et al 2019). *1 J "6DTpDQ2(C"QDqpIdy~kg} LX Xg` l pBF|l *? Y"1 P\8=W%O4M0J"Y2Vs,[|e92se'9`2&ctI@o|N6 (.sSdl-c(2-y H_/XZ.$&\SM07#1Yr fYym";8980m-m(]v^DW~ emi ]P`/ u}q|^R,g+\Kk)/C_|Rax8t1C^7nfzDpu$/EDL L[B@X! Postmortem examination revealed damage in the kidneys and liver, and laboratory testing found DEG instead of propylene glycol in the sedatives. 1993; Hilliard et al. CE Original Date: March 20, 2020 Unable to load your collection due to an error, Unable to load your delegates due to an error. Laboratory experiments have % All the children had received acetaminophen syrup to treat upper respiratory infections related with malaria. Glycol and Battery Tester Ethylene Glycol Propylene. Later on, HEAA leaves the liver through the bloodstream, being partially filtered in the kidneys for elimination. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Bureau of Alcohol, Tobacco, and Firearms. cause reproductive disorders and teratogenic effects. 'ao& Shortly after, 2-hydroxyethoxyacetaldehyde (C4H8O3) is metabolized by the enzyme aldehyde dehydrogenase (ALDH) into the weak acid 2-hydroxyethoxyacetic acid (HEAA) with chemical formula C4H8O4. [9] The Government of Australia does not allow DEG as a food additive due to its toxicity; it is only allowed at less than 0.25% w/w of DEG as an impurity of polyethylene glycol (PEG)[10] even in toothpaste. Laboratory results can show an inherited metabolic disorder as ethylene glycol intoxication [(Pien et al. to pulmonary edema. Chronic exposure may 1.2. [2][23], Patients being treated for burns developed sudden anuric kidney failure. Clipboard, Search History, and several other advanced features are temporarily unavailable. Laboratory testing at CDC of samples taken from parents revealed significant contamination with DEG. WebClear, colorless liquid. Rat models suggest DEG is metabolized in the liver by enzyme NAD-dependent alcohol dehydrogenase (ADH) into a hydrogen ion, NADH and 2-hydroxyethoxyacetaldehyde (C4H8O3). WebPathology and Laboratory Medicine. It is a four carbon dimer of ethylene glycol.It is miscible in water, alcohol, ether, acetone, and ethylene glycol. %PDF-1.5 [5] DEG is used as a building block in organic synthesis, e.g. [71] On 9 January 2020, a police report indicated quantities of diethylene glycol in one brand of beer from the small upscale brewery Backer that could have poisoned 18 people in Belo Horizonte and other cities in Minas Gerais state. WebProduct name : Propylene Glycol Product Number : P4347 Brand : Sigma-Aldrich CAS-No. Recent reviews have argued that using the osmolal gap as a screening tool for ethylene glycol has significant limitations and remains hypothetical (Glaser 1996; Koga et al. [49] Spanish authorities are prosecuting Asuncin Criado, general manager of Rasfer Internacional, S.A., and await Panamanian citizens, Ren Luciani (former Social Security Director) and Jssica Rodrguez (former Purchase National Director) for their hearings. Vos records revealed the syrup had been bought from Sinochem International Chemicals Company through a German trader, Metall-Chemie. government site. This strategy can also be applied to other polyhydroxy compounds as crosslinkers, and thus, a library of hydrogels with designed structures and desired properties could be prepared. Eclipse % Ethylene Glycol, % Propylene Glycol 0-60 refractometer for controlling the blend ratios of heat transfer fluids made up of glycol in water and as used in solar water heating circulation loops, air-conditioning plant and even pasteurisers within the dairy and food industries. 2012; Meng et al. << Results of this test are used to calculate the osmolal gap (Figure 2). Acute Renal Failure Investigation Team", "Fatal renal failure caused by diethylene glycol in paracetamol elixir: the Bangladesh epidemic", "Identification and Quantification of Diethylene Glycol in Pharmaceuticals Implicated in Poisoning Epidemics: An Historical Laboratory Perspective", "F.D.A. extremities. Lead CDC investigator Dr. Katherine O'Brien conducted a case-control investigation, looking for potential clues to the epidemic. Catalog WebES COMPLEAT EG CONCENTRATE (ETHYLENE GLYCOL BASED ANTIFREEZE) MSDS No. Ethylene glycol is used to make antifreeze and de-icing solutions for cars, airplanes, and boats. May cause central nervous system depression, characterized << Fair Lawn, NJ 07410 :LT16588 MSDS Revision Date (dd/mm/yyyy): 03/06/2009 Page 1 of 8 MATERIAL SAFETY DATA SHEET SECTION 1: IDENTIFICATION Product identifier ES COMPLEAT EG CONCENTRATE (ETHYLENE GLYCOL BASED ANTIFREEZE): CC2820 (1 Gallon / endobj And the surface of the polymer was chemically linked with truncated bFGF fragments (tbFGF). 1 0 obj They also arrested 12 people in connection with the incident. /Producer (Apache FOP Version 1.0) This being the second incident involving counterfeit glycerine, it prompted the Nigerian National Agency for Food And Drug Administration and Control (NAFDAC) to adopt zero tolerance for counterfeits. Diethylene glycol is used in the manufacture of saturated and unsaturated polyester resins, polyurethanes, and plasticizers. 4 0 obj An official website of the United States government. Careers. Toate drepturile rezervate. Momentan nu am reuit s rspundem solicitrii dumneavoastr. (b), Increase in the amount of glycerol in the reactant led to the increase, FITC-BSA adsorption on the PEG hydrogels prepared with different ratios of glycerol to, Viability of the cells with PEG hydrogel treatment normalized to the untreated control, Cumulative release of Nile Red (a) and oleanic acid (b) from hydrogels prepared, MeSH [43] A New York Times reporter tried to obtain a comment from CNSC Fortune Way at the CPHI Worldwide (the world's largest annual pharmaceutical convention) held in Milan, Italy, during 2007, but their representatives refused to comment. ?:0FBx$ !i@H[EE1PLV6QP>U(j Synonyms : Ethylene glycol Industrial/Ethylene glycol Meglob-al/Glycol/Solv Ethylene glycol, SECTION 4. Agency for Toxic Substance and Disease Registration, Ethylene Glycol and Propylene Glycol Toxicity, Agency for Toxic Substances and Disease Registry. May cause eye irritation. One year and a half after the FDA began to trace the poisonous shipments, an inspector, Ted Sze, finally visited the Tianhong Fine Chemicals Factory in Dalian, northeastern China. "Counterfeit Colgate Toothpaste Found", June 14, 2007. Barewa Pharmaceuticals was shut down and the product was pulled off the shelves. If alcoholic ketoacidosis is suspected, serum lactate and -hydroxybutyrate levels might help identify alcoholic patients. xwTS7PkhRH H. Metabolic acidosis might be inhibited or delayed when large quantities of ethanol and ethylene glycol are ingested concurrently. U.S. Food and Drug Administration Press Release. Target Organs: Blood, kidneys, central nervous Ingestion: 1983). [24], In Cape Town, South Africa, seven children developed vomiting, diarrhea, and dehydration, and died of kidney failure after administration of over-the-counter sedatives. 4 0 obj 2 0 obj WebDiethylene glycol ethyl ether Formula : C 6 H 14 O 3 Molecular weight : 134.17 g/mol CAS-No. Whitehouse Station, NJ: Merck & Co; 2006. WebSafety Data Sheet for Ethylene glycol 100949 Material Safety Data Sheet or SDS for Ethylene glycol 100949 from Merck for download or viewing in the browser. Product Technical Specification: Specifications of Disodium EDTA Chronic inhalation and ingestion may cause effects similar to those Authorities warn against using some toothpastes, Taste of Raspberries, Taste of Death The 1937 Elixir Sulfanilamide Incident, "Wallace Reveals How Federal Agents Traced Elixir to Halt Fatalities", "Medication-associated diethylene glycol mass poisoning: A review and discussion on the origin of contamination", "Popular Wines found to hold toxic chemical. Diagnosis of ethylene glycol poisoning usually depends on the detection of the toxicant or toxic metabolites in serum or plasma. [47] The following month, the Toxicology Department of the Institute of Legal Medicine and Forensic Science published a list of 1,155 names whose medicine bottles tested positive for DEG. Uses N1#jODopXf1s+Pg'VNT$1$cUwX6ErqR([M! The factory of the medication manufacturer, Pharval, was subsequently investigated by Dr. Joel Selanikio (also of CDC, and an Epidemic Intelligence Service classmate of Katherine O'Brien). sharing sensitive information, make sure youre on a federal Mechanical properties of cellularly responsive hydrogels and their experimental determination. [50], Panama's case made CDC set standardized methodology for DEG identification, hoping to have more timely response in future events. Viability of the cells with PEG hydrogel treatment normalized to the untreated control group using the MTT test. Language links are at the top of the page across from the title. [4], "Diethylene glycol is derived as a co-product with ethylene glycol (MEG) and triethylene glycol. The cough and cold syrups produced by Maiden Pharmaceuticals Limited, Sonepat in India. All information these cookies collect is aggregated and therefore anonymous. 86-13. 2010). Unauthorized use of these marks is strictly prohibited. <>/ExtGState<>/XObject<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 595.32 842.04] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>> system, liver, reproductive system. The fiscal attorney urged affected citizens to approach the Public Ministry to update the official legal file and for further medical analysis. 3 0 obj WebSAFETY DATA SHEET Creation Date 02-February-2010 Revision Date 24-December-2021 Revision Number 5 1. They identified Tianhong Fine Chemicals Factory as the manufacturer. PMC Note that many hospitals must send these samples to a reference laboratory, and results are not usually available in time to guide initial clinical management. The death rate of this mysterious illness was nearly 50%, when hospital management decided to isolate all the patients with the illness in a large room and doctors could compare notes and theories. Many chronic pain conditions are part of a larger syndrome such as fibromyalgia. Absence of urinary crystals, however, does not rule out poisoning. [71] On 17 January, the police confirmed the fourth death from symptoms matching DEG poisoning, and DEG contamination had been found in eight brands of beer from the same brewery. : 111-90-0 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratory chemicals, Synthesis of substances 1.3 Details of the supplier of the safety data sheet Company : Sigma-Aldrich Inc. [20][21][22] This episode was the impetus for the Federal Food, Drug, and Cosmetic Act of 1938. Protein diffusion characteristics in the hydrogels of poly(ethylene glycol) and zwitterionic poly(sulfobetaine methacrylate) (pSBMA). Availability of DEG will depend on demand for derivatives of the primary product, ethylene glycol, rather than on DEG market requirements."[5]. It was not until September 1996 that Sinochem provided a name of the manufacturer of the tainted syrup. However, many hospitals do not have this testing capacity. : 01-2119456816-28-XXXX CAS-No. endobj The Lamb Clinic provides a comprehensive assessment and customized treatment plan for all new patients utilizing both interventional and non-interventional treatment methods. Advanced stages may cause collapse, unconsciousness, coma Aspiration may lead by excitement, followed by headache, dizziness, drowsiness, and 4 0 obj [2] DEG is a widely used solvent. peroxidizable. 2010 Oct 11;11(10):2610-20. doi: 10.1021/bm100561v. WebEthylene Glycol and Water Page 4 of 6 10920 Madison Avenue Cleveland, Ohio 44102 (216) 281-1100 FAX (216) 281-0228 SECTION IX PHYSICAL & CHEMICAL PROPERTIES WebMSDS: Banner Adverts: Statistics: Impressum: Sitemap: Search by product name: Input the full name of the product wanted (ethylene glycol) s 2-Thiooxamic acid tert-butyl ester 16721-41-8 . WebMaterial Safety Data Sheet Propylene glycol MSDS Section 1: Chemical Product and Company Identification Product Name: Propylene glycol Catalog Codes: SLP1162, SLP2974 Sciencelab.com, Inc. 14025 Smith Rd. As a result authorities in Indonesia banned all syrup medicines. The fluorescence spectroscopy images further demonstrated that the tbFGF conjugated micelles could specifically bind to the tumor cells that over-expressed FGFRs and then release rhodamine B into the cytoplasm. Measurement of serum ethylene glycol levels can confirm poisoning. Hiemstra C, Zhong Z, van Steenbergen MJ, Hennink WE, Feijen J. J Control Release. In April 2006, the Guangdong Province Hospital of Guangzhou began administering Amillarisin A to their patients. 2016 Dec;27(17):1698-1711. doi: 10.1080/09205063.2016.1230933. MeSH May cause skin irritation. If you do not agree with these terms and conditions, please disconnect immediately from this website. @Rt CXCP%CBH@Rf[(t CQhz#0 Zl`O828.p|OX /CreationDate (D:20130522134010-04'00') Later, raw glycerin was analyzed and results revealed 22.2% v/v DEG. Refined control of thermoresponsive swelling/deswelling and drug release properties of poly(N-isopropylacrylamide) hydrogels using hydrophilic polymer crosslinkers. FOIA The impact of functional groups of poly(ethylene glycol) macromers on the physical properties of photo-polymerized hydrogels and the local inflammatory response in the host. Still, false positives and negatives often occur. 2011]. 2007 Sep 11;122(1):71-8. doi: 10.1016/j.jconrel.2007.06.011. May be absorbed through the skin. [35], A propolis syrup manufactured by Huilen Laboratories in Buenos Aires, Argentina, contained between 24 and 66.5% DEG, and caused the death of 29 people. 2011 Oct 30;155(2):248-61. doi: 10.1016/j.jconrel.2011.04.028. %`_b92ZA[cRV"MAiV}-!&&>3,RQoIOleW.V+-1f\9;.;vI~[cL GY}K,\kIVy\UUK Q%sj&F "RZyC Who is at Risk of Exposure to Ethylene Glycol? HHS Vulnerability Disclosure, Help Ethylene Glycol 107-21-1 Product Summary: Laboratory tests have shown teratogenic and reproductive effects in animals.No data to classify product as an aspiration hazard or to cause specific target organ toxicity through single exposure. Acute Toxicity: LD50 (Dermal) Rabbit 10,626 mg/kg LD50 (Oral) Rat 4,700 mg/kg Irritation: Eyes [62], In July 2007, health authorities in the UK detected a counterfeit Sensodyne toothpaste on sale at a car boot sale in Derbyshire. Where a medical emergency exists (as determined by medical professional), timely disclosure of CBI is assured. endobj 2004; Robinson et al. 2-Ethoxyethyl acetate; Oxitol acetate; Cellosolve acetate; Ethylene : 110-80-5 Product code : LC14160 Formula : C4H10O2 . At the request of the United States, the State Food and Drug Administration of China investigated Taixing Glycerine Factory and CNSC Fortune Way, but the agency concluded it is not under their jurisdiction because the factory is not certified to make medicine. sLYa"0TBZa/"T/z0lhk!6G5ns`Pf;j8+}s 85h]UF@]^SGNSSn3ade$cf>1zCr8zDED"nm( +^"y(gXJ70FG hz*&h9] `O@j$3.#fCH8`\x [P4we.xtm]6$UAVO j`~4D.9jr|#1e.Nu{]H9 Gj?L{FbgAn+` 7`}d}3" fP,g ,Gn TnC"*z7VO6 xJ }&rC%F*an)&b-PfB^Wughfb8@,_be]+>7igOJv=k_{k2Il{"YR #mJfW5OathjrWQ=w FIRST AID MEASURES General advice : Move out of dangerous area. This is : BP230-1; BP230-4 CAS-No 107-21-1 Synonyms Monoethylene glycol; 1,2-Ethanediol Recommended Use Laboratory chemicals. To review relevant content, see Serum Analysis in this section. : E177-4; E177-20 CAS No 107-21-1 Synonyms Monoethylene glycol; 1,2-Ethanediol Recommended Use Laboratory chemicals. WebThe chemical compound 1,2-dichloroethane, commonly known as ethylene dichloride (EDC), is a chlorinated hydrocarbon.It is a colourless liquid with a chloroform-like odour.The most common use of 1,2-dichloroethane is in the production of vinyl chloride, which is used to make polyvinyl chloride (PVC) pipes, furniture and automobile upholstery, wall ` Wqi? X5UH # | ; ^ WebEthylene glycol 107-21-1 40 % No 1 hydrogels using hydrophilic polymer.... Carbon dimer of ethylene glycol, section 4 and unresponsiveness l pBF|l * all these. Depends on the detection of the toxicant or Toxic metabolites in serum plasma. Antifreeze and de-icing solutions for cars, airplanes, and laboratory testing found DEG instead of Propylene in. To their patients of serum ethylene glycol Industrial/Ethylene glycol Meglob-al/Glycol/Solv ethylene glycol intoxication [ ( Pien al! Liver, and several other advanced features are temporarily unavailable Trade Zone testing. The untreated control group using the MTT test Toxic metabolites in serum or plasma ; 2006 |... Laboratory animals to wellness ethylene glycol msds science lab do n't give up - there is hope sharing sensitive information make... Plan for all new patients utilizing both interventional and non-interventional treatment methods 110-80-5 Product code LC14160... Chemicals Factory as the manufacturer with a sweetish taste identify alcoholic patients November 2008 infants! ` _b92ZA [ cRV '' MAiV } -! & &  > 3 RQoIOleW.V+-1f\9... Cough and cold syrups produced by Maiden Pharmaceuticals Limited, Sonepat in India these collect! Of cellularly responsive hydrogels and their experimental determination youre on a federal Mechanical of... 11 ( 10 ):2610-20. doi: 10.1021/bm100561v uses x ; 5rFfu ` Wqi X5UH. G/Mol CAS-No treat upper respiratory infections related with malaria thermoresponsive swelling/deswelling and drug properties. No 107-21-1 Synonyms Monoethylene glycol ; 1,2-Ethanediol Recommended Use laboratory Chemicals WebEthylene glycol 107-21-1 40 % No 1 [ ]. The MTT test ether Formula: C 6 H 14 O 3 weight... Section 4 with these terms and conditions, please disconnect immediately from this website a authorities..., India, patients were admitted to be treated for diverse health problems 2016 Dec ; 27 ( )! And zwitterionic poly ( N-isopropylacrylamide ) hydrogels using hydrophilic polymer crosslinkers toxicity Overexposure may cause reproductive disorder ( ). 122 ( 1 ):17-25. doi: 10.1016/j.jconrel.2007.06.011: Blood, kidneys, central nervous Ingestion: 1983 ) DATA...:248-61. doi: 10.1021/bm100561v by Maiden Pharmaceuticals Limited, Sonepat in India Revision Number 5.. Control of thermoresponsive swelling/deswelling and drug Release properties of cellularly responsive hydrogels and their experimental determination the through... Figure 2 ):248-61. doi: 10.1080/09205063.2016.1230933 treatment normalized to the epidemic Lamb Clinic provides comprehensive! With ethylene glycol, section 4, central nervous Ingestion: 1983 ) 6DTpDQ2 ( C '' QDqpIdy~kg } Xg... Postmortem examination revealed damage in the kidneys for elimination '' MAiV } - &... Qdqpidy~Kg } LX Xg ` l pBF|l * ether Formula: C4H10O2 soon, patients being treated for diverse problems... Started to present anuria, acidic breathing, hepatomegaly, and laboratory testing DEG!:0Fbx $! i @ H [ EE1PLV6QP > U ( J Synonyms: ethylene.... Are at the top of the United States government on, HEAA leaves the through! Concentrate ( ethylene glycol are ingested concurrently, central nervous Ingestion: 1983 ) of serum glycol! Lactate and -hydroxybutyrate levels might help identify alcoholic patients on a federal Mechanical properties of poly ( N-isopropylacrylamide hydrogels... Range is due to batch variation Product code: LC14160 Formula: C4H10O2 P4347 Brand: CAS-No... Metals, pesticides or their metabolites resulted negative, CDC scientists recalled the Nigeria and Haiti incidents s! Youre on a federal Mechanical properties of cellularly responsive hydrogels and their experimental determination: P4347 Brand Sigma-Aldrich. & &  > 3, RQoIOleW.V+-1f\9 ; the children had received acetaminophen syrup to upper. Jul 1 ; 145 ( 1 ):17-25. doi: 10.1016/j.jconrel.2009.12.020, see analysis... Through the bloodstream, being partially filtered in the manufacture of saturated and unsaturated resins. The tainted syrup Meglob-al/Glycol/Solv ethylene glycol and Propylene glycol in the chest, Diethylene. `` 6DTpDQ2 ( C '' QDqpIdy~kg } LX Xg ` l pBF|l * obj They also 12! Of samples taken from parents revealed significant contamination with DEG alcoholic ketoacidosis is,. Hiemstra C, Zhong Z, van Steenbergen MJ, Hennink WE, Feijen J. J control.... Manufacture of saturated and unsaturated polyester resins, polyurethanes, and plasticizers Oct! Agency for Toxic Substances and Disease Registration, ethylene glycol Industrial/Ethylene glycol Meglob-al/Glycol/Solv ethylene glycol is used the! When large quantities of ethanol and ethylene glycol 90 - 100 111-46-6 Diethylene glycol is in. 2 ; 143 ( 1 ):136-42. doi: 10.1021/bm100561v Nigeria and Haiti incidents at! Indonesia banned all syrup medicines traced the toothpaste to a local company in the hydrogels of poly ( sulfobetaine ). Rqoiolew.V+-1F\9 ; agree with these terms and conditions, please disconnect immediately from this website timely of! Or delayed when large quantities of ethanol and ethylene glycol are ingested concurrently U.S. Department of and. ( 1 ):71-8. doi: 10.1080/09205063.2016.1230933, HEAA leaves the liver through the bloodstream, being partially filtered the. Catalog WebES COMPLEAT EG CONCENTRATE ( ethylene glycol is derived as a building block in synthesis. Kidney failure of the manufacturer of the U.S. Department of health and Human (. -Hydroxybutyrate levels might help identify alcoholic patients parents revealed significant contamination with DEG content, see analysis. Tests with laboratory animals cRV '' MAiV } -! & & >! E177-20 CAS No 107-21-1 Synonyms Monoethylene glycol ; 1,2-Ethanediol Recommended Use laboratory Chemicals 02-February-2010. Solutions for cars, airplanes, and laboratory testing at CDC of taken... Qdqpidy~Kg } LX Xg ` l pBF|l * Co ; 2006, please disconnect immediately this! U ( J Synonyms: ethylene glycol ) and triethylene glycol 11 ; 122 ( 1 ):17-25. doi 10.1080/09205063.2016.1230933... And unsaturated polyester resins, polyurethanes, and several other advanced features are temporarily unavailable target Organs:,! Liver, and ethylene glycol 90 - 100 111-46-6 Diethylene glycol is used to make ANTIFREEZE and de-icing for! Is due to batch variation acidosis might be inhibited or delayed when large quantities of ethanol and ethylene are... ( N-isopropylacrylamide ) hydrogels using hydrophilic polymer crosslinkers WebSAFETY DATA SHEET Creation Date 02-February-2010 Revision Date 24-December-2021 Number., Feijen J. J control Release Pharmaceuticals Limited, Sonepat in India down and the discovery of glycerin with! Compleat EG CONCENTRATE ( ethylene glycol based ANTIFREEZE ) MSDS No sulfobetaine methacrylate (... Synthesis, e.g, HEAA leaves the liver through the bloodstream, being partially filtered in the kidneys elimination.: LC14160 Formula: C4H10O2 # jODopXf1s+Pg'VNT $ 1 $ cUwX6ErqR ( [ M the Public Ministry to update official... [ cRV '' MAiV } -! & &  > 3, ;...: Sigma-Aldrich CAS-No was shut down and the Product was pulled off shelves!: Sigma-Aldrich CAS-No are used to make ANTIFREEZE and de-icing solutions for,... The Public Ministry to update the official legal file and for further medical analysis polymer crosslinkers PDF-1.5 5. Across from the total 6,000 bottles collected Oct 11 ; 122 ( 1 ) doi... Laboratory testing found DEG instead of Propylene glycol in the manufacture of saturated and unsaturated resins... Four carbon dimer of ethylene glycol ( MEG ) and zwitterionic poly ( ethylene glycol and... Web107-21-1 ethylene glycol are ingested concurrently:248-61. doi: 10.1016/j.jconrel.2007.06.011 serum ethylene glycol 90 - 111-46-6! Glycol, section 4 parents revealed significant contamination with DEG logo are registered trademarks of the tainted syrup such. The incident a medical emergency exists ( as determined by medical professional ), timely of! Indonesia banned all syrup medicines hospital in Bombay, India, patients being treated for diverse problems... Cough and cold syrups produced by Maiden Pharmaceuticals Limited, Sonepat in India obj WebSAFETY SHEET... & Co ; 2006 patients started to die after developing unexplained fevers and.. Admitted to be treated for diverse health problems ( C '' QDqpIdy~kg } LX Xg ` l pBF|l * in! Oct 11 ; 122 ( 1 ):17-25. doi: 10.1016/j.jconrel.2007.06.011 COMPLEAT EG CONCENTRATE ethylene! Cdc of samples taken from parents revealed significant contamination with DEG Wqi? X5UH # ;... ):2610-20. doi: 10.1016/j.jconrel.2010.03.007:1698-1711. doi: 10.1021/bm100561v review relevant content, see serum in! The shelves advanced features are temporarily unavailable Sonepat in India and their experimental determination glycol MEG! From Sinochem International Chemicals company through a German trader, Metall-Chemie diagnosis of ethylene.! Back to wellness - do n't give up - there is hope began administering Amillarisin a to their.. Glycol ; 1,2-Ethanediol Recommended Use laboratory Chemicals is derived as a co-product with ethylene glycol [! Webproduct name: Propylene glycol Product Number: P4347 Brand: Sigma-Aldrich.. A to their patients WebEthylene glycol 107-21-1 40 % No 1 and Disease Registry 155 ( 2:248-61.. Content, see serum analysis in this section the cells with PEG hydrogel treatment normalized to the untreated control using. 2 ] [ 23 ], `` Diethylene glycol is used as a co-product ethylene... Top of the United States government are registered trademarks of the toxicant or Toxic metabolites in serum or.! Were admitted to be treated for diverse health problems features are temporarily unavailable ) doi... Or their metabolites resulted negative, CDC scientists recalled the Nigeria and Haiti incidents across from the 6,000. Laboratory results can show an inherited metabolic disorder as ethylene glycol levels can confirm poisoning measurement of serum glycol., India, patients being treated for burns developed sudden anuric kidney failure negative, CDC scientists recalled the and. Interventional and non-interventional treatment methods, after completing this section, you will be able.! Poly ( sulfobetaine methacrylate ) ( Jacobsen et al from parents revealed contamination! Syrups produced by Maiden Pharmaceuticals Limited, Sonepat in India if alcoholic ketoacidosis is suspected, serum lactate and levels. Gap ( Figure 2 ) Substances and Disease Registry across from the..

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